Anti-coagulum Cardiac Ablation Catheter

Cardiac atrial fibrillation ablation procedures have been shown to be associated with coagulum (blood clot) that forms on electrodes during radiofrequency ablation. This coagulum in turn may give rise to stroke and other embolic complications, a significant risk for health for patients undergoing such procedures. The invention by the Mayo physicians has demonstrated that application of a small negative charge during ablation significantly reduces the fibrin formation and subsequent clot formation. This has been conclusively demonstrated on the bench, as well as in large animal models, and published in a leading peer-reviewed journal. (Lim B, Venkatachalam KL, Jahangir A, Johnson SB, Asirvatham SJ. J Cardiovasc Electrophysiol. 2008 Aug;19(8):843-50.). We are conducting research and development activities in order to develop this concept into a commercial product.

Orthopedic Tissue Tension Sensor

Soft tissue balancing has been identified as a key element of the total knee arthroplasty (TKA) procedures for improving patient outcomes. However, the handling of soft tissue balance remains a challenge, relying largely on a surgeon’s subjective feel and relative level of experience and lacking quantative tools to reliably and consistently balancing soft tissues for TKA and other major orthopedic surgeries. However, existing methods for measuring soft tissue tension intra-operatively are inadequate: inaccurate, expensive, complicated, invasive and/or lacking in versatility. Currently, there is no easy to use, non-invasive and inexpensive tool available that allows surgeons to measure soft tissue tension in order to balance the soft tissues.

With the overall goal of a low-cost method to improve patient outcomes, a tool that would allow for simple, safe, and effective measurement of soft tissue tension would have several advantages. Particularly, such a tool would enable surgeons to quantify and modify/optimize soft tissue tension during surgery to ultimately achieve better patient outcomes. Leading engineers from the University of Minnesota developed the Company’s tension measurement technology.

For more information, see Highlight Orthopedic's website.